CDH17 Is a More Sensitive Marker for Gastric Adenocarcinoma Than CK20 and CDX2
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چکیده
منابع مشابه
CDH17 is a Highly Specific and More Sensitive Marker Than CK20 and CDX2 in Colon Adenocarcinoma and in Stomach Adenocarcinoma
CDH17 stained 100% (99/99) of colon adenocarcinoma, whereas CK20 and CDX2 stained 92% (91/99) and 96% (95/99), respectively (Figure 1A-C and Figure 2A-C). In stomach adenocarcinoma, CDH17 stained 73% (50/69), CK20 28% (19/69) and CDX2 16% (11/69) (Figure 3A-C) (Table 1). CDH17 was positive in 35% (10/29) of pancreatic ductal cell adenocarcinomas (Figure 4A) (data not shown). All cases of pancre...
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Cadherin 17 (CDH17) is a cell adhesion molecule expressed in intestinal epithelium and transcriptionally regulated by CDX2. We compared the usefulness of CDH17 as an immunohistochemical intestinal marker to that of CDX2 in gastrointestinal and extragastrointestinal carcinomas and nonneoplastic tissues. Nonneoplastic intestinal and pancreatic duct epithelia were CDH17-positive. Most esophageal (...
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objective(s): prostate cancer is the world’s leading cause of cancer and the second cause of cancer-related death in men after lung cancer. differentiation of prostate adenocarcinoma from benign prostate lesions and hyperplasia sometimes cannot be done on the basis of morphologic findings. considering the fact that in the prostate adenocarcinoma there is no basal cell layer, basal cell markers ...
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ژورنال
عنوان ژورنال: Archives of Pathology & Laboratory Medicine
سال: 2016
ISSN: 0003-9985,1543-2165
DOI: 10.5858/arpa.2015-0404-oa